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Panic disorder

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2007-12-24No history Add My version 
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Mind map Panic disorder (from MedMaps.co.uk) - the online mind map resource for medical students and doctors. Psychiatry. Medicine. 
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Panic disorder

Characteristics

Causes

Genetic predisposition

extra-sensitive amygdala

Excess caffeine

hyperventilation

induces panic attacks in lab

Drugs/Alcohol

excess or withdrawal

Definition DSM IV

Panick attacks

recurrent attacks

minutes in duration

unexpected

No stimulus

followed by 1 month of (at least 1):

Avoidance of situations

reduce quality of life

affect functioning

Alcohol abuse

change in behaviour

exclusion of organic disorder

eg hyperthyroidism

Prevalence

2-3% in Europe

>

25-44 years

Associations

Mitral valve prolapse

40-50%

persists after cure

not causant

hypertension

depression

50% with PD develop depression

50% with depression develop PD

Migraine

Asthma

Agoraphobia

Pathogenesis

Prognosis

some relapse

majority OK with Rx

Complications

Agoraphobia

Anticipatory fear

loss of control

reluctancy to be alone

Depression

Suicide

Increased risk

esp. if depressed

Increased risk cardiovascular mortality

Biopsychosocial Management

Investigations

Challenge tests

Sodium lactate infusion

CO2 breathing

Treatment

CBT

NICE

7-14 hours

within 4 months

also via internet

"Fear Fighter" programme

Antidepressants

SSRIs first line

may worsen anxiety initially

use small doses

slow withdrawal

6 months after symptom free

Imipramine & chlomipramine

if all else fails

Behaviour change

Self help

avoid caffeine

exercise

muscle relaxation

Breathing exercises

Benzodiazepines

extreme cases only

short-term

Differential

PTSD

Obsessive-compulsive disorder

Agoraphobia

Simple phobia

Social phobia

Depression

S&S

Constant Fear

dying

lose control

madness

"fear of fear"

Acute panick attacks

Autonomics

palpitations

sweating

trembling

abdo disturbance

dizzy

Depersonalisation

Derealisation

chest pain

choking

paraesthesias

chills or hot flashes

Avoidance

threatening situations

Alcohol/drug abuse